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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TERBINAFINE

TERBINAFINE


ATC D01AE15
ATC D01BA02

DERMATOLOGICALS
ANTIFUNGAL
ALLYLAMINES
INHIBITS BIOSYNTHESIS OF ERGOSTEROL

TOPICAL ORAL

Cmax 23.5 NANOMOLAR

Tmax 2 HOUR

F 70 PERCENT

VD 818 LITER (EQN)

PPB 99 PERCENT

Cl 27 LITER / HOUR

HT 21 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

SQUALENE EPOXIDASE ENZYME

Squalene epoxidase UNIPROT Q4JEY0

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