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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
AZELASTINE

AZELASTINE


ATC R01AC03
ATC R06AX19
ATC S01GX07

RESPIRATORY SYSTEM
H1 ANTIHISTAMINE ANTAGONIST
PHTHALAZINONE DERIVATIVE

NASAL OPHTHALMIC

Tmax 2.5 HOUR

F 40 PERCENT

VD 942 LITER

PPB 88 PERCENT

Cl 32.5 LITER / HOUR

HT 22 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN WATER

HISTAMINE H1 RECEPTOR

Histamine H1 receptor UNIPROT P35367 HRH1

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