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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
AZELASTINE

AZELASTINE


ATC R01AC03
ATC R06AX19
ATC S01GX07

RESPIRATORY SYSTEM
H1 ANTIHISTAMINE ANTAGONIST
PHTHALAZINONE DERIVATIVE

NASAL OPHTHALMIC

Tmax 2.5 HOUR

F 40 PERCENT

VD 942 LITER

PPB 88 PERCENT

Cl 32.5 LITER / HOUR

HT 22 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN WATER

HISTAMINE H1 RECEPTOR

HISTAMINE H1 RECEPTOR ANTAGONIST CHEMBL231 HISTAMINE H1 RECEPTOR P35367 HISTAMINE H1 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTORANSM (in French)

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