| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ITRACONAZOLE
| ITRACONAZOLE | ANTIINFECTIVES | ORAL INJECTION | Cmax 3.2 MICROMOLAR Tmax 4.6 HOUR F 55 PERCENT VD 796 LITER PPB 99.8 PERCENT Cl 22.8 LITER / HOUR HT 64 HOUR SOLUBILITY INSOLUBLE IN WATER | CYTOCHROME P450 | Lanosterol 14-alpha demethylase UNIPROT P10613 ERG11 more at DrugCentral | EMA | |||
