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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BISOPROLOL

BISOPROLOL


ATC C07AB07
ATC C07FX04
ATC C07FB07
ATC C07BB07
ATC C09BX02
ATC C09BX04
ATC C09BX05

CARDIOVASCULAR
ANTIHYPERTENSIVE
ADRENERGIC BETA-1 ANTAGONIST
SYMPATHOLYTICS
ADRENERGIC BETA-2 INVERSE AGONIST

ORAL

Cmax 0.21 MICROMOLAR (20 MG)

Tmax 3 HOUR

F 80 PERCENT

VD 156 LITER (65 KILOGRAM)

PPB 30 PERCENT

Cl 14.4 LITER / HOUR (65 KILOGRAM)

HT 10 HOUR

SOLUBILITY SOLUBLE IN WATER

BETA-1 ADRENERGIC RECEPTOR
ADRENERGIC BETA-2 RECEPTOR

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1

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