| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ADENOSINE
| ADENOSINE | NATURAL MOLECULE (link) CARDIOVASCULAR | INJECTION INTRAVENOUS | SOLUBILITY SOLUBLE IN WATER | A1 AND A2 ADENOSINE RECEPTOR ADENOSINE DEAMINASE ADENOSINE KINASE PDB 4OGR (CRYSTAL STRUCTURE OF P-TEFB COMPLEX WITH AFF4 AND TAT) LIGAND CODE = ADN (link to the list of PDB complexes) Download experimental 3D coordinates of ADN with added hydrogens | Adenosine receptor A2a UNIPROT P29274 ADORA2A -- Adenosine receptor A1 UNIPROT P30542 ADORA1 more at DrugCentral | EMA | |||
