Cheminformatic Tools and Databases for Pharmacology

session 7910 - Total of 2 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FOSINOPRIL (has an active metabolite)

FOSINOPRIL


ATC C09AA09
ATC C09BA09

CARDIOVASCULAR
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS
ANTIHYPERTENSIVE AGENTS

ORAL

F 36 PERCENT

SOLUBILITY SOLUBLE IN WATER

ANGIOTENSIN-CONVERTING ENZYME

Angiotensin-converting enzyme UNIPROT P12821 ACE

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FOSINOPRILAT (is an active metabolite)

FOSINOPRILAT


ATC C09AA09
ATC C09BA09

CARDIOVASCULAR
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS
ANTIHYPERTENSIVE AGENTS

-

Tmax 3 HOUR

VD 8.45 LITER (65 KILOGRAM)

PPB 99.4 PERCENT

Cl 1.95 LITER / HOUR

HT 12 HOUR

ANGIOTENSIN-CONVERTING ENZYME

PDB 7Z6Z (CRYSTAL STRUCTURE OF ANGIOTENSIN-1 CONVERTING ENZYME N-DOMAIN IN COMPLEX WITH FOSINOPRILAT)

LIGAND CODE = KS8 (link to the list of PDB complexes)

Download experimental 3D coordinates of KS8 with added hydrogens

Angiotensin-converting enzyme UNIPROT P12821 ACE

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |