CLOMIPRAMINE (has an active metabolite) | CLOMIPRAMINE | ATC N06AA04
NERVOUS SYSTEM ANTIDEPRESSANT ANTIOBSESSIONAL SEROTONIN UPTAKE INHIBITORS | ORAL | Cmax 693 NANOMOLAR Tmax 4 HOUR VD 845 LITER (65 KILOGRAM) PPB 97 PERCENT Cl 31.9 LITER / HOUR (65 KILOGRAM) HT 32 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | SEROTONIN TRANSPORTER PDB 4MMA (CRYSTAL STRUCTURE OF LEUBAT (DELTA13 MUTANT) IN COMPLEX WITH CLOMIPRAMINE) LIGAND CODE = CXX (link to the list of PDB complexes) Download experimental 3D coordinates of CXX with added hydrogens | Sodium-dependent serotonin transporter UNIPROT P31645 SLC6A4 -- Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2 more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |