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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PRAVASTATIN

PRAVASTATIN


ATC C10AA03
ATC C10BX02
ATC C10BA03

CARDIOVASCULAR
ANTIHYPERLIPIDEMIC
HMG-COA REDUCTASE INHIBITOR
ANTICHOLESTEREMIC AGENTS

ORAL

Cmax 62.5 NANOMOLAR

Tmax 1.25 HOUR

F 17 PERCENT

VD 29.9 LITER (65 KILOGRAM)

PPB 50 PERCENT

Cl 54.6 LITER / HOUR (65 KILOGRAM)

HT 1.8 HOUR

SOLUBILITY SOLUBLE IN WATER

3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE

HMG-COA REDUCTASE INHIBITOR CHEMBL402 HMG-COA REDUCTASE P04035 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE HOMO SAPIENS ENZYME REDUCTASEANSM (in French)

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