Cheminformatic Tools and Databases for Pharmacology

session 90472 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FELODIPINE

FELODIPINE


ATC C08CA02
ATC C07FB02
ATC C09BB05

CARDIOVASCULAR
VASODILATOR
ANTIHYPERTENSIVE
ANTI-ARRHYTHMIA AGENTS
CALCIUM CHANNEL BLOCKERS
DIHYDROPYRIDINES
S ENANTIOMER MORE ACTIVE

ORAL

Cmax 2 NANOMOLAR

Tmax 4.5 HOUR

F 20 PERCENT

VD 650 LITER (65 KILOGRAM)

PPB 99 PERCENT

Cl 48 LITER / HOUR

HT 14 HOUR

SOLUBILITY INSOLUBLE IN WATER

VOLTAGE-DEPENDENT CALCIUM L-CHANNEL

Voltage-dependent L-type calcium channel subunit alpha-1C UNIPROT Q13936 CACNA1C -- Voltage-dependent L-type calcium channel subunit alpha-1D UNIPROT Q01668 CACNA1D

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |