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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
OLSALAZINE (has an active metabolite)

OLSALAZINE


ATC A07EC03

METABOLISM
ANTIINFLAMMATORY
GASTROINTESTINAL AGENTS
TREATMENT OF ULCERATIVE COLITIS

ORAL

Cmax 6.2 MICROMOLAR

Tmax 1 HOUR

F 2.4 PERCENT

VD 4.5 LITER (65 KILOGRAM)

PPB 99 PERCENT

Cl 4.6 LITER / HOUR (65 KILOGRAM)

HT 0.9 HOUR

SOLUBILITY SOLUBLE IN WATER

ARACHIDONATE 5-LIPOXYGENASE INHIBITOR CHEMBL215 ARACHIDONATE 5-LIPOXYGENASE P09917 ARACHIDONATE 5-LIPOXYGENASE HOMO SAPIENS ENZYME REDUCTASEANSM (in French)

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