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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OLSALAZINE (has an active metabolite)
| OLSALAZINE | METABOLISM | ORAL | Cmax 6.2 MICROMOLAR Tmax 1 HOUR F 2.4 PERCENT VD 4.5 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 4.6 LITER / HOUR (65 KILOGRAM) HT 0.9 HOUR SOLUBILITY SOLUBLE IN WATER | Arachidonate 5-lipoxygenase UNIPROT P09917 ALOX5 -- Peroxisome proliferator-activated receptor gamma UNIPROT P37231 PPARG more at DrugCentral | EMA | ||||
