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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DIETHYLCARBAMAZINE DISCONTINUED

DIETHYLCARBAMAZINE


ATC P02CB02

ANTIPARASITIC
ANTHELMINTIC
FILARICIDES
INTERFERES WITH CYCLOOXYGENASE AND LIPOXYGENASE PATHWAYS

ORAL

Cmax 3.2 MICROMOLAR (PMID11865970)

Tmax 2.7 HOUR

VD 533 LITER

Cl 2 LITER / HOUR (65 KILOGRAM)

HT 11.4 HOUR

PROSTAGLANDIN H SYNTHASE (PMID19426666)

NEMATODE GABA-A RECEPTOR POSITIVE MODULATOR CHEMBL2364676 NEMATODE GABA-A RECEPTOR E1FVX6 UNCHARACTERIZED PROTEIN ONCHOCERCIDAE UNCLASSIFIEDANSM (in French)

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