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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MEFLOQUINE

MEFLOQUINE


ATC P01BC02
ATC P01BF02

ANTIPARASITIC
ANTIMALARIAL
STRUCTURAL ANALOG OF QUININE

ORAL

Cmax 5.29 MICROMOLAR

Tmax 17 HOUR

F 85 PERCENT

VD 1300 LITER

PPB 98 PERCENT

Cl 1.8 LITER / HOUR

HT 504 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

POTASSIUM CHANNEL (PMID21502926)

FERRIPROTOPORPHYRIN IX INHIBITOR CHEMBL613897 FERRIPROTOPORPHYRIN IX PLASMODIUM FALCIPARUMANSM (in French)

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