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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LISINOPRIL
| LISINOPRIL |
CARDIOVASCULAR | ORAL | Tmax 7 HOUR F 25 PERCENT VD 57.8 LITER PPB 0 PERCENT Cl 4.6 LITER / HOUR HT 42 HOUR SOLUBILITY SOLUBLE IN WATER | ANGIOTENSIN-CONVERTING ENZYME PDB 1O86 (CRYSTAL STRUCTURE OF HUMAN ANGIOTENSIN CONVERTING ENZYME IN COMPLEX WITH LISINOPRIL.) LIGAND CODE = LPR (link to the list of PDB complexes) Download experimental 3D coordinates of LPR with added hydrogens | Angiotensin-converting enzyme UNIPROT P12821 ACE more at DrugCentral | EMA | |||
