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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NIZATIDINE

NIZATIDINE


ATC A02BA04

METABOLISM
HISTAMINE H2 RECEPTOR ANTAGONIST
ANTIHISTAMINE
ANTI-ULCER AGENTS

ORAL

Cmax 10.8 MICROMOLAR (300 MILLIGRAM)

Tmax 1.75 HOUR

F 70 PERCENT

VD 74.7 LITER (65 KILOGRAM)

PPB 35 PERCENT

Cl 50 LITER / HOUR

HT 1.5 HOUR

SOLUBILITY SOLUBLE IN WATER

HISTAMINE H2 RECEPTOR

HISTAMINE H2 RECEPTOR ANTAGONIST CHEMBL1941 HISTAMINE H2 RECEPTOR P25021 HISTAMINE H2 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTORANSM (in French)

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