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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NIZATIDINE

NIZATIDINE


ATC A02BA04

METABOLISM
HISTAMINE H2 RECEPTOR ANTAGONIST
ANTIHISTAMINE
ANTI-ULCER AGENTS

ORAL

Cmax 10.8 MICROMOLAR (300 MILLIGRAM)

Tmax 1.75 HOUR

F 70 PERCENT

VD 74.7 LITER (65 KILOGRAM)

PPB 35 PERCENT

Cl 50 LITER / HOUR

HT 1.5 HOUR

SOLUBILITY SOLUBLE IN WATER

HISTAMINE H2 RECEPTOR

Histamine H2 receptor UNIPROT P25021 HRH2

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