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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NICARDIPINE
| NICARDIPINE | CARDIOVASCULAR | ORAL INJECTION INTRAVENOUS | Cmax 277 NANOMOLAR (40 MILLIGRAM EVERY 8 HOUR) Tmax 1 HOUR F 35 PERCENT VD 539 LITER (65 KILOGRAM) PPB 95 PERCENT Cl 26 LITER / HOUR (65 KILOGRAM) HT 4.1 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | VOLTAGE-DEPENDENT CALCIUM CHANNEL | Voltage-gated L-type calcium channel UNIPROT Q01668 CACNA1D more at DrugCentral | EMA | |||
