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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GLUCONOLACTONE
| GLUCONOLACTONE | FOOD ADDITIVE E575 USED AS A SEQUESTRANT | IRRIGATION | PDB 2E40 (CRYSTAL STRUCTURE OF INTRACELLULAR FAMILY 1 BETA-GLUCOSIDASE BGL1A FROM THE BASIDIOMYCETE PHANEROCHAETE CHRYSOSPORIUM IN COMPLEX WITH GLUCONOLACTONE) LIGAND CODE = LGC (link to the list of PDB complexes) Download experimental 3D coordinates of LGC with added hydrogens | Lysosomal acid glucosylceramidase UNIPROT P04062 GBA1 more at DrugCentral | EMA | ||||
