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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ISRADIPINE

ISRADIPINE


ATC C08CA03

CARDIOVASCULAR
CA CHANNEL ANTAGONIST
ANTIHYPERTENSIVE
VASODILATOR AGENTS

ORAL

Cmax 53.9 NANOMOLAR (20 MILLIGRAM)

Tmax 1.5 HOUR

F 19.5 PERCENT

VD 195 LITER (65 KILOGRAM)

PPB 95 PERCENT

Cl 84 LITER / HOUR

HT 8 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

VOLTAGE-DEPENDENT CALCIUM CHANNEL

VOLTAGE-GATED L-TYPE CALCIUM CHANNEL BLOCKER CHEMBL2095229 VOLTAGE-GATED L-TYPE CALCIUM CHANNEL O60840 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1F HOMO SAPIENS ION CHANNEL VGC VG CAANSM (in French)

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