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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PINACIDIL DISCONTINUED

PINACIDIL


ATC C02DG01
ATC C02LX01

CARDIOVASCULAR
ATP-DEPENDENT POTASSIUM CHANNEL AGONIST
ANTIHYPERTENSIVE

ORAL

Cmax 408 MICROMOLAR (30 MILLIGRAM) (PMID6653652)

F 57 PERCENT

VD 91 LITER (65 KILOGRAM) (PMID4007251)

Cl 31.5 LITER / HOUR (EQN)

HT 2 HOUR (PMID4007251)

ATP-DEPENDENT POTASSIUM CHANNEL

SULFONYLUREA RECEPTOR 2, O60706 ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 HOMO SAPIENS TRANSPORTER NTPASE ATP BINDING CASSETTE MRPANSM (in French)

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