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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PERGOLIDE DISCONTINUED

PERGOLIDE


ATC N04BC02

NERVOUS SYSTEM
DOPAMINE RECEPTOR AGONIST
ANTIDYSKINETICS
ANTIPARKINSON AGENTS
NEUROPROTECTIVE AGENTS
ERGOT DERIVATIVE

ORAL

Tmax 2.5 HOUR

VD 14000 LITER (PMID15965310)

PPB 90 PERCENT

Cl 462 LITER / HOUR (EQN)

HT 21 HOUR

D1 DOPAMINE RECEPTOR
D2 DOPAMINE RECEPTOR

DOPAMINE RECEPTOR AGONIST CHEMBL2096905 DOPAMINE RECEPTOR P14416 D(2) DOPAMINE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR DOPAMINE RECEPTORANSM (in French)

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