| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PERGOLIDE DISCONTINUED
| PERGOLIDE | NERVOUS SYSTEM | ORAL | Tmax 2.5 HOUR VD 14000 LITER (PMID15965310) PPB 90 PERCENT Cl 462 LITER / HOUR (EQN) HT 21 HOUR | D1 DOPAMINE RECEPTOR D2 DOPAMINE RECEPTOR | D(2) dopamine receptor UNIPROT P14416 DRD2 -- D(1A) dopamine receptor UNIPROT P21728 DRD1 more at DrugCentral | EMA | |||
