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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CLOBETASOL PROPIONATE
| CLOBETASOL PROPIONATE | DERMATOLOGICALS | TOPICAL OPHTHALMIC | Cmax 0.12 NANOMOLAR SOLUBILITY INSOLUBLE IN WATER | GLUCOCORTICOID RECEPTOR PDB 7LAD (CLOBETASOL PROPIONATE BOUND TO CYP3A5) LIGAND CODE = XRD (link to the list of PDB complexes) Download experimental 3D coordinates of XRD with added hydrogens | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | |||
