Cheminformatic Tools and Databases for Pharmacology

session 6989 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TRANEXAMIC ACID

TRANEXAMIC ACID


ATC B02AA02

BLOOD
HEMOSTATIC
ANTIFIBRINOLYTIC
TREATMENT OF CYCLIC HEAVY MENSTRUAL BLEEDING
COMPETITIVE INHIBITOR OF PLASMINOGEN ACTIVATION

ORAL INJECTION INTRAVENOUS

Cmax 104 MICROMOLAR (MULTIPLE DOSE)

Tmax 3 HOUR

F 45 PERCENT

VD 25.3 LITER (65 KILOGRAM)

PPB 3 PERCENT

Cl 6.7 LITER / HOUR

HT 11 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

PLASMINOGEN

PDB 1B2I (KRINGLE 2 DOMAIN OF HUMAN PLASMINOGEN: NMR SOLUTION STRUCTURE OF TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID (AMCHA) COMPLEX)

LIGAND CODE = AMH (link to the list of PDB complexes)

Download experimental 3D coordinates of AMH with added hydrogens

PLASMINOGEN INHIBITOR CHEMBL1801 PLASMINOGEN P00747 PLASMINOGEN HOMO SAPIENS ENZYME PROTEASE SERINE PAS S1AANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |