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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEVOBETAXOLOL
| LEVOBETAXOLOL BETAXOLOL |
CARDIOVASCULAR | OPHTHALMIC ORAL | Cmax 70.3 NANOMOLAR Tmax 3 HOUR F 89 PERCENT VD 312 LITER (65 KILOGRAM) PPB 50 PERCENT Cl 13.26 LITER / HOUR (65 KILOGRAM) HT 18 HOUR SOLUBILITY SOLUBLE IN WATER | BETA-1 ADRENERGIC RECEPTOR | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 more at DrugCentral | EMA | |||
