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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PROPAFENONE

PROPAFENONE


ATC C01BC03

CARDIOVASCULAR
1C ANTIARRHYTHMIC
CHANNEL BLOCKER

ORAL

Tmax 3.5 HOUR

F 12 PERCENT

VD 252 LITER

PPB 95 PERCENT

Cl 57 LITER / HOUR

HT 21 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

POTASSIUM VOLTAGE-GATED CHANNEL
SODIUM CHANNEL

BETA-2 ADRENERGIC RECEPTOR ANTAGONIST CHEMBL210 BETA-2 ADRENERGIC RECEPTOR P07550 BETA-2 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTORANSM (in French)

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