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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PROPAFENONE
| PROPAFENONE | CARDIOVASCULAR | ORAL | Tmax 3.5 HOUR F 12 PERCENT VD 252 LITER PPB 95 PERCENT Cl 57 LITER / HOUR HT 21 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | POTASSIUM VOLTAGE-GATED CHANNEL SODIUM CHANNEL | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A more at DrugCentral | EMA | |||
