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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HYDROMORPHONE (is an active metabolite)
| HYDROMORPHONE |
NERVOUS SYSTEM | INJECTION ORAL INTRAMUSCULAR INTRAVENOUS SUBCUTANEOUS | Cmax 20 NANOMOLAR Tmax 0.73 HOUR VD 302.9 LITER PPB 13 PERCENT Cl 117.6 LITER / HOUR HT 2.3 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | MU-TYPE OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 more at DrugCentral | EMA | |||
