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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEVOCARNITINE
| LEVOCARNITINE | METABOLISM | ORAL INJECTION | Cmax 80 MICROMOLAR Tmax 3.3 HOUR F 15 PERCENT VD 100.4 LITER (EQN) PPB 0 PERCENT Cl 4 LITER / HOUR HT 17.4 HOUR SOLUBILITY READILY SOLUBLE IN WATER | MITOCHONDRIAL CARNITINE/ACYLCARNITINE CARRIER PROTEIN ORGANIC CATION/CARNITINE TRANSPORTER PDB 2H3U (CRYSTAL STRUCTURE OF MURINE CARNITINE ACETYLTRANSFERASE IN COMPLEX WITH CARNITINE AND COA) LIGAND CODE = 152 (link to the list of PDB complexes) Download experimental 3D coordinates of 152 with added hydrogens | Carnitine O-palmitoyltransferase 1 liver isoform UNIPROT P50416 CPT1A more at DrugCentral | EMA | |||
