| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NALTREXONE
| NALTREXONE |
NERVOUS SYSTEM | ORAL INTRAMUSCULAR | Cmax 2 NANOMOLAR Tmax 2 HOUR F 22 PERCENT VD 1350 LITER PPB 21 PERCENT Cl 210 LITER / HOUR HT 4 HOUR SOLUBILITY INSOLUBLE IN WATER | MU-TYPE OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 -- Kappa-type opioid receptor UNIPROT P41145 OPRK1 more at DrugCentral | EMA | |||
