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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CICLOPIROX
| CICLOPIROX | DERMATOLOGICALS | TOPICAL | Cmax 386 NANOMOLAR F 1.3 PERCENT HT 1.7 HOUR | PDB 6J10 (CICLOPIROX INHIBITS HEPATITIS B VIRUS SECRETION BY BLOCKING CAPSID ASSEMBLY) LIGAND CODE = B4O (link to the list of PDB complexes) Download experimental 3D coordinates of B4O with added hydrogens | Unknown more at DrugCentral | EMA | |||
