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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BUSPIRONE

BUSPIRONE


ATC N05BE01

NERVOUS SYSTEM
5HT1A RECEPTOR AGONIST
ANXIOLYTIC
SEROTONIN AGONISTS

ORAL

Cmax 15.5 NANOMOLAR

Tmax 1 HOUR

F 90 PERCENT

PPB 86 PERCENT

HT 2.5 HOUR

SOLUBILITY SOLUBLE IN WATER

5-HYDROXYTRYPTAMINE 1A RECEPTOR

SEROTONIN 1A (5-HT1A) RECEPTOR PARTIAL AGONIST CHEMBL214 SEROTONIN 1A (5-HT1A) RECEPTOR P08908 5-HYDROXYTRYPTAMINE RECEPTOR 1A HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTORANSM (in French)

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