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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NABILONE

NABILONE


ATC A04AD11

METABOLISM
ANXIOLYTIC
ANTIEMETIC
CANNABINOID RECEPTOR 1 AGONIST
TREATMENT OF NAUSEA AND VOMITING INDUCED BY CANCER CHEMOTHERAPY
SIMILAR TO THE ACTIVE INGREDIENT FOUND IN NATURALLY OCCURRING CANNABIS SATIVA L.

ORAL

Cmax 5.3 NANOMOLAR

Tmax 2 HOUR

VD 812 LITER (65 KILOGRAM)

Cl 281.3 LITER / HOUR (EQN)

HT 2 HOUR

SOLUBILITY LESS THAN 0.5 MILLIGRAM / LITER

CANNABINOID RECEPTOR 1

CANNABINOID CB1 RECEPTOR AGONIST CHEMBL218 CANNABINOID CB1 RECEPTOR P21554 CANNABINOID RECEPTOR 1 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL LIPID-LIKE LIGAND RECEPTOR CANNABINOID RECEPTORANSM (in French)

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