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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FLUTAMIDE (has an active metabolite)
| FLUTAMIDE | ANTINEOPLASTIC | ORAL | Cmax 282.6 NANOMOLAR Tmax 1.3 HOUR F 100 PERCENT PPB 95 PERCENT HT 7.8 HOUR | ANDROGEN RECEPTOR | ANDROGEN RECEPTOR ANTAGONIST CHEMBL1871 ANDROGEN RECEPTOR P10275 ANDROGEN RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C4 | ANSM (in French) | |||
