Cheminformatic Tools and Databases for Pharmacology

session 95063 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ALPROSTADIL

ALPROSTADIL


ATC C01EA01
ATC G04BE01

CARDIOVASCULAR
SMOOTH MUSCLE RELAXANT
VASODILATOR
FIBRINOLYTIC AGENTS
PLATELET AGGREGATION INHIBITORS
PROSTAGLANDIN E1 (PGE1)

INJECTION URETHRAL

Cmax 47 PICOMOLAR

Tmax 0.058 HOUR

F 98 PERCENT

VD 1593 LITER (EQN)

PPB 93 PERCENT

Cl 6900 LITER / HOUR

HT 0.16 HOUR

SOLUBILITY SOLUBLE IN WATER

PDB 3WHX (CRYSTAL STRUCTURE OF ANTI-PROSTAGLANDIN E2 FAB FRAGMENT PGE1 COMPLEX)

LIGAND CODE = XPG (link to the list of PDB complexes)

Download experimental 3D coordinates of XPG with added hydrogens

PROSTANOID EP1 RECEPTOR AGONIST CHEMBL1811 PROSTANOID EP1 RECEPTOR P34995 PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL LIPID-LIKE LIGAND RECEPTOR PROSTANOID RECEPTORANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |