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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRAZODONE
| TRAZODONE | NERVOUS SYSTEM | ORAL | Cmax 3.2 MICROMOLAR Tmax 9 HOUR VD 33.8 LITER (65 KILOGRAM) PPB 92 PERCENT Cl 5.4 LITER / HOUR (65 KILOGRAM) HT 10 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | 5-HYDROXYTRYPTAMINE 2A RECEPTOR 5-HYDROXYTRYPTAMINE 2C RECEPTOR ALPHA 1-ADRENERGIC RECEPTOR | Sodium-dependent serotonin transporter UNIPROT P31645 SLC6A4 -- 5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A more at DrugCentral | EMA | |||
