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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TRAZODONE

TRAZODONE


ATC N06AX05

NERVOUS SYSTEM
ANTIDEPRESSANT
ANTI-ANXIETY AGENTS
TRIAZOLOPYRIDINE
INHIBITS NEURONAL REUPTAKE OF SEROTONIN
5-HYDROXYTRYPTAMINE 2A/2C RECEPTOR ANTAGONIST
ALPHA 1-ADRENERGIC RECEPTOR ANTAGONIST

ORAL

Cmax 3.2 MICROMOLAR

Tmax 9 HOUR

VD 33.8 LITER (65 KILOGRAM)

PPB 92 PERCENT

Cl 5.4 LITER / HOUR (65 KILOGRAM)

HT 10 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

5-HYDROXYTRYPTAMINE 2A RECEPTOR
5-HYDROXYTRYPTAMINE 2C RECEPTOR
ALPHA 1-ADRENERGIC RECEPTOR

SEROTONIN 2A (5-HT2A) RECEPTOR ANTAGONIST CHEMBL224 SEROTONIN 2A (5-HT2A) RECEPTOR P28223 5-HYDROXYTRYPTAMINE RECEPTOR 2A HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTORANSM (in French)

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