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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NADOLOL
| NADOLOL | CARDIOVASCULAR | ORAL | VD 123.5 LITER (65 KILOGRAM) PPB 86 PERCENT Cl 11.3 LITER / HOUR (65 KILOGRAM) HT 22 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | BETA-1 ADRENERGIC RECEPTOR BETA-2 ADRENERGIC RECEPTOR | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2 more at DrugCentral | EMA | |||
