Cheminformatic Tools and Databases for Pharmacology

session 87072 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BROMOCRIPTINE

BROMOCRIPTINE


ATC G02CB01
ATC N04BC01

NERVOUS SYSTEM
ANTIPARKINSONIAN
ANTIDYSKINETICS
DOPAMINE AGONISTS
ERGOT DERIVATIVE
SIGNIFICANTLY REDUCES PLASMA LEVELS OF PROLACTIN

ORAL

Cmax 711 PICOMOLAR

Tmax 2.5 HOUR

F 80 PERCENT

VD 61 LITER

PPB 93 PERCENT

Cl 7 LITER / HOUR (EQN)

HT 6 HOUR

D(2) DOPAMINE RECEPTOR

PDB 5VCG (CRYSTAL STRUCTURE OF THE CYSTEINE DEPLETED CYP3A4 BOUND TO BROMOERGOCRYPTINE)

LIGAND CODE = 08Y (link to the list of PDB complexes)

Download experimental 3D coordinates of 08Y with added hydrogens

5-HYDROXYTRYPTAMINE RECEPTOR 1A P08908 5-HYDROXYTRYPTAMINE RECEPTOR 1A HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTORANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |