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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TRIAZOLAM

TRIAZOLAM


ATC N05CD05

NERVOUS SYSTEM
ANXIOLYTIC
BENZODIAZEPINES
GABA MODULATORS
A TRIAZOLOBENZODIAZEPINE HYPNOTIC AGENT

ORAL

Cmax 17.5 NANOMOLAR

Tmax 2 HOUR

VD 37.7 LITER (65 KILOGRAM)

PPB 90 PERCENT

Cl 11.7 LITER / HOUR (65 KILOGRAM)

HT 3.5 HOUR

SOLUBILITY POORLY SOLUBLE IN WATER

GAMMA-AMINOBUTYRIC-ACID RECEPTOR (GABA)

GABA-A RECEPTOR ANION CHANNEL POSITIVE ALLOSTERIC MODULATOR CHEMBL2093872 GABA-A RECEPTOR ANION CHANNEL P14867 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 HOMO SAPIENS ION CHANNEL LGIC GABAAANSM (in French)

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