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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SCOPOLAMINE

SCOPOLAMINENATURAL MOLECULE (link)


ATC A04AD01
ATC N05CM05
ATC S01FA02
ATC A04AD51

METABOLISM
ANTISPASMODIC
ANTICHOLINERGIC
ANTIMUSCARINICS
MYDRIATICS
A BELLADONNA ALKALOID
PREVENTION OF NAUSEA
NONSELECTIVE MUSCARINIC RECEPTOR ANTAGONIST

TRANSDERMAL

Cmax 906 NANOMOLAR (PMID2762223)

Tmax 4 HOUR

F 29.4 PERCENT

VD 201.5 LITER (65 KILOGRAM)

PPB 10 PERCENT (PMID9725548)

Cl 62.4 LITER / HOUR (65 KILOGRAM)

HT 9.5 HOUR

MUSCARINIC ACETYLCHOLINE RECEPTOR

MUSCARINIC ACETYLCHOLINE RECEPTOR M1 ANTAGONIST CHEMBL216 MUSCARINIC ACETYLCHOLINE RECEPTOR M1 P11229 MUSCARINIC ACETYLCHOLINE RECEPTOR M1 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ACETYLCHOLINE RECEPTORANSM (in French)

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