Cheminformatic Tools and Databases for Pharmacology

session 93466 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CYCLOBENZAPRINE

CYCLOBENZAPRINE


ATC M03BX08

MUSCULO-SKELETAL
MUSCLE RELAXANT (SKELETAL)
RELIEVES SKELETAL MUSCLE SPASM OF LOCAL ORIGIN WITHOUT INTERFERING WITH MUSCLE FUNCTION
5-HT2 RECEPTOR ANTAGONIST (PMID12498911)
STRUCTURAL ANALOG OF TRICYCLIC ANTIDEPRESSANTS

ORAL

Cmax 167 NANOMOLAR

Tmax 7.1 HOUR

F 44 PERCENT

VD 1939 LITER (EQN)

Cl 42 LITER / HOUR

HT 32 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

5-HYDROXYTRYPTAMINE 2A RECEPTOR

SEROTONIN 2A (5-HT2A) RECEPTOR ANTAGONIST CHEMBL224 SEROTONIN 2A (5-HT2A) RECEPTOR P28223 5-HYDROXYTRYPTAMINE RECEPTOR 2A HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTORANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |