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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LORAZEPAM
| LORAZEPAM | NERVOUS SYSTEM | ORAL INJECTION | Cmax 62 NANOMOLAR F 90 PERCENT VD 84.5 LITER (65 KILOGRAM) PPB 91 PERCENT Cl 4.3 LITER / HOUR HT 14 HOUR SOLUBILITY ALMOST INSOLUBLE IN WATER | GAMMA-AMINOBUTYRIC-ACID RECEPTOR | GABA-A receptor alpha-1,beta-3,gamma-2 UNIPROT P14867 GABRA1 more at DrugCentral | EMA | |||
