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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GLIPIZIDE
| GLIPIZIDE | METABOLISM | ORAL | Tmax 2 HOUR F 100 PERCENT VD 11 LITER PPB 98.5 PERCENT Cl 2.1 LITER / HOUR (65 KILOGRAM) HT 3 HOUR SOLUBILITY INSOLUBLE IN WATER | ATP-SENSITIVE POTASSIUM CHANNEL OF THE PANCREATIC B-CELL | Sulfonylurea receptor 1, Kir6.2 UNIPROT Q09428 ABCC8 more at DrugCentral | EMA | |||
