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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
LACTULOSE

LACTULOSE


ATC A06AD11
ATC A06AD61

METABOLISM
SYNTHETIC DISACCHARIDE
A COLONIC ACIDIFIER FOR TREATMENT AND PREVENTION OF PORTAL-SYSTEMIC ENCEPHALOPATHY
REDUCES THE BLOOD AMMONIA LEVELS

ORAL RECTAL

SOLUBILITY FREELY SOLUBLE IN WATER

EVOLVED BETA-GALACTOSIDASE SUBUNIT ALPHA

PDB 3W9T (PORE-FORMING CEL-III)

LIGAND CODE = W9T (link to the list of PDB complexes)

Download experimental 3D coordinates of W9T with added hydrogens

Unknown - more at DrugCentralANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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