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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MEBENDAZOLE

MEBENDAZOLE


ATC P02CA01
ATC P02CA51

ANTIPARASITIC
ANTHELMINTIC
ANTINEMATODAL AGENTS
INHIBITS THE FORMATION OF THE WORMS' MICROTUBULES

ORAL

VD 78 LITER (65 KILOGRAM)

PPB 91 PERCENT

Cl 58.5 LITER / HOUR (65 KILOGRAM)

HT 1.1 HOUR

SOLUBILITY LESS THAN 0.05 PERCENT SOLUBLE IN WATER

TUBULIN

TUBULIN INHIBITOR CHEMBL2364704 TUBULIN C4PKY4 BETA-TUBULIN ISOFORM 1 TAENIIDAE STRUCTURALANSM (in French)

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