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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MEBENDAZOLE
| MEBENDAZOLE | ANTIPARASITIC | ORAL | VD 78 LITER (65 KILOGRAM) PPB 91 PERCENT Cl 58.5 LITER / HOUR (65 KILOGRAM) HT 1.1 HOUR SOLUBILITY LESS THAN 0.05 PERCENT SOLUBLE IN WATER | TUBULIN PDB 7OGN (CRYSTAL STRUCTURE OF T2R-TTL -MEBENDAZOLE COMPLEX) LIGAND CODE = V95 (link to the list of PDB complexes) Download experimental 3D coordinates of V95 with added hydrogens | Tubulin UNIPROT C4PKY4 -- Tubulin UNIPROT F1L005 more at DrugCentral | EMA | |||
