IBUPROFEN | IBUPROFEN | ATC N02AJ08 ATC N02AJ23 ATC C01EB16 ATC G02CC01 ATC M01AE01 ATC M02AA13 ATC R02AX02 ATC M01AE51 ATC N02AJ19
MUSCULO-SKELETAL ANALGESICS ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL (NSAIDS) CYCLOOXYGENASE INHIBITORS TREATMENT OF A HAEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS IN PRETERM NEWBORN INFANTS (DRUG FOR RARE DISEASE IN EUROPE) | ORAL INTRAVENOUS | Cmax 92 MICROMOLAR VD 7.8 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 2.9 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | PROSTAGLANDIN G/H SYNTHASE 1 PROSTAGLANDIN G/H SYNTHASE 2 PDB 3R8G (AKR1C3 COMPLEX WITH IBUPROFEN) LIGAND CODE = IZP (link to the list of PDB complexes) Download experimental 3D coordinates of IZP with added hydrogens | Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2 -- Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1 more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |