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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DANTROLENE

DANTROLENE


ATC M03CA01

MUSCULO-SKELETAL
MUSCLE RELAXANT
RYANODINE RECEPTOR 1 ANTAGONIST

ORAL INJECTION INTRAVENOUS

VD 24 LITER (65 KILOGRAM)

Cl 1.6 LITER / HOUR (65 KILOGRAM)

HT 6 HOUR

RYANODINE RECEPTOR 1

RYANODINE RECEPTOR 1 ANTAGONIST CHEMBL1846 RYANODINE RECEPTOR 1 P21817 RYANODINE RECEPTOR 1 HOMO SAPIENS ION CHANNEL LGIC RYRANSM (in French)

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