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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DINOPROST DISCONTINUED
| DINOPROST | GENITO | INJECTION | Cmax 1.2 NANOMOLAR Tmax 0.6 HOUR SOLUBILITY IN WATER 1.3 MILLIGRAM / MILLILITER | PROSTAGLANDIN E2 RECEPTOR EP2 PDB 8IUK (CRYO-EM STRUCTURE OF THE PGF2-ALPHA-BOUND HUMAN PTGFR-GQ COMPLEX) LIGAND CODE = UGU (link to the list of PDB complexes) Download experimental 3D coordinates of UGU with added hydrogens | Prostaglandin F2-alpha receptor UNIPROT P43088 PTGFR more at DrugCentral | EMA | |||
