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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DOPAMINE (is an active metabolite)
| DOPAMINE | NATURAL MOLECULE (link) CARDIOVASCULAR | INJECTION | HT 0.03 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | BETA ADRENERGIC RECEPTOR DOPAMINE RECEPTOR CATECHOL O-METHYLTRANSFERASE (COMT) MONOAMINE OXIDASE PDB 4XP1 (X-RAY STRUCTURE OF DROSOPHILA DOPAMINE TRANSPORTER BOUND TO NEUROTRANSMITTER DOPAMINE) LIGAND CODE = LDP (link to the list of PDB complexes) Download experimental 3D coordinates of LDP with added hydrogens | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 more at DrugCentral | EMA | |||
