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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METOLAZONE
| METOLAZONE | CARDIOVASCULAR | ORAL | VD 104 LITER (65 KILOGRAM) PPB 95 PERCENT Cl 5.4 LITER / HOUR (65 KILOGRAM) HT 14 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | NA-CL COTRANSPORTER (NCC) | Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3 more at DrugCentral | EMA | |||
