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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FLOXURIDINE (has an active metabolite)

FLOXURIDINE


ATC L01BC09

ANTINEOPLASTIC
ANTIMETABOLITES
INTERFERE WITH THE SYNTHESIS OF DNA AND RNA
RAPIDLY CATABOLIZED TO 5-FLUOROURACIL

INJECTION

SOLUBILITY FREELY SOLUBLE IN WATER

DNA

THYMIDYLATE SYNTHASE INHIBITOR CHEMBL1952 THYMIDYLATE SYNTHASE P04818 THYMIDYLATE SYNTHASE HOMO SAPIENS ENZYME TRANSFERASEANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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