Cheminformatic Tools and Databases for Pharmacology

session 32688 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PROCARBAZINE

PROCARBAZINE


ATC L01XB01

ANTINEOPLASTIC
TREATMENT OF STAGE III AND IV HODGKIN'S DISEASE
MAY INHIBIT TRANSMETHYLATION OF METHYL GROUPS OF METHIONINE INTO T-RNA
HYDROGEN PEROXIDE FORMED DURING THE AUTO-OXIDATION OF THE DRUG MAY ATTACK PROTEIN SULFHYDRYL GROUPS CONTAINED IN RESIDUAL PROTEIN WHICH IS TIGHTLY BOUND TO DNA

ORAL

Tmax 1 HOUR

F 100 PERCENT

HT 0.16 HOUR

SOLUBILITY SOLUBLE BUT UNSTABLE IN WATER

DNA

DNA INHIBITOR CHEMBL2311221 DNA HOMO SAPIENSANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |