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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CYCLOTHIAZIDE DISCONTINUED
| CYCLOTHIAZIDE | CARDIOVASCULAR | ORAL | GLUTAMATE RECEPTOR 2 PDB 5WEO (ACTIVATED GLUA2 COMPLEX BOUND TO GLUTAMATE, CYCLOTHIAZIDE, AND STZ IN DIGITONIN) LIGAND CODE = CYZ (link to the list of PDB complexes) Download experimental 3D coordinates of CYZ with added hydrogens | Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3 more at DrugCentral | EMA | ||||
