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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CHLOROQUINE
| CHLOROQUINE | ANTIPARASITIC | ORAL INJECTION | Cmax 0.513 MICROMOLAR (PMID6661356) VD 9100 LITER (65 KILOGRAM) PPB 55 PERCENT Cl 16 LITER / HOUR (65 KILOGRAM) HT 570 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | DNA LACTATE DEHYDROGENASE PDB 4V2O (STRUCTURE OF SAPOSIN B IN COMPLEX WITH CHLOROQUINE) LIGAND CODE = CLQ (link to the list of PDB complexes) Download experimental 3D coordinates of CLQ with added hydrogens | Unknown more at DrugCentral | EMA | |||
